The Most Common Cancer Types in the U.S.
Cancer is a potentially deadly disease that’s common worldwide. In the U.S. alone, the approximate number of cases in 2025 of just the four most common types—breast, prostate, lung cancer and colorectal—is expected to exceed one million.
10 Most Common Cancers in the U.S.
Nearly every person is affected by cancer in their lifetime—either through their own diagnosis or that of a loved one. According to the National Cancer Institute, the expected number of new cancer cases and deaths in 2025 for the 10 most common cancers (excluding nonmelanoma skin cancers) are shown below.
| Cancer Type | Estimated New Cases (2025) | Estimated Deaths (2025) |
|---|---|---|
| Breast cancer (female) | 319,750 | 42,680 |
| Prostate cancer | 313,780 | 35,770 |
| Lung cancer (including bronchus) | 226,650 | 124,730 |
| Colon and rectal cancer (combined) | 154,270 | 52,900 |
| Melanoma | 104,960 | 8,430 |
| Bladder cancer | 84,870 | 17,420 |
| Kidney cancer | 80,980 | 14,510 |
| Non-Hodgkin lymphoma | 80,350 | 19,390 |
| Endometrial cancer | 69,120 | 13,860 |
| Leukemia (all types) | 66,890 | 23,540 |
Most Common Cancers Diagnosed in Women
More than half of all new cancer diagnoses in women fall into three categories:
- Breast cancer
- Lung cancer
- Colorectal cancer
Breast cancer is the most common cancer diagnosed in women and the most common cancer overall in the United States, excluding nonmelanoma skin cancers.
Most Common Cancers Diagnosed in Men
Approximately 48% of new cancer diagnoses in men fall into three types:
- Prostate cancer
- Lung cancer
- Colorectal cancer
Prostate cancer is the most common cancer diagnosed in men and the second most common cancer overall in the U.S., excluding nonmelanoma skin cancers.
Summary and Conclusion
Few diagnoses are more concerning to patients and families than cancer. Ongoing research continues to improve prevention, detection, and treatment options across many cancer types.
Understanding your personal cancer risk and taking steps to reduce it can play an important role in protecting your long-term health.
Baptist Health Offers World-Class Cancer Services
If you are concerned about cancer or have received a diagnosis, Baptist Health offers comprehensive cancer care from experienced specialists. Our team can help you understand your diagnosis, treatment options, and next steps with clarity and compassion.
Contact your Baptist Health oncologist to learn more about our cancer care services. We’re here for you. If you don't have a Baptist Health provider, you can find one by visiting our provider directory.
